Welcome to the Paul F. Glenn Center for Biology of Aging Research at MIT

PAUL F. GLENN 1930–2020

The Paul F. Glenn Center for Biology of Aging Research at MIT is sad to announce the recent passing of Paul F. Glenn, a pioneer in the field of aging. Paul was a visionary, who recognized as a young man that aging represented one of humankind’s greatest challenges, and one that was amenable to scientific study and eventual intervention. He realized that investment in scientific research on aging would pay dividends in improving the quality of life for people everywhere.  Paul started the Glenn Foundation for Medical Research (GFMR) in 1965, and was an early advocate for the creation of the National Institute on Aging at NIH.
I knew Paul for about 15 years, and funding from the GFMR has been key to the research efforts of the Guarente, Tsai, and Amon labs at MIT. The GFMR has figured in no small part in the field of sirtuins/NAD+, one of the promising interventions to slow the effects of aging and forestall diseases.  Paul was a gentle soul, sharp of mind and soft of voice, but he radiated a steadfast purposefulness that drove the great success of the GFMR and aging research, generally. I will miss his kind smile and encouraging words greatly. He was truly one of a kind.
from the Director, Leonard P. Guarente

The Paul F. Glenn Center for Biology of Aging Research at MIT focuses on basic aspects of aging in a multi-tiered approach to provide novel ways to intervene in the aging process and potentially ameliorate health decline and diseases that occur at advancing ages. Projects include aging in adult stem cells, brain and muscle (Guarente lab), role of DNA damage and DNA repair in Alzheimer’s disease and brain aging (Tsai lab), and the role of chromosomal aneuploidy in aging (Amon lab). All told, this basic research will lead to new strategies to extend the period of robust health, which will provide considerable societal benefit.

The research work is carried out at 3 labs at MIT --

The Glenn Foundation for Medical Research generously funds this research work. Further information on what each lab is doing can be found on our Research page.